Robust model-based transformation and averaging of diffusion weighted images – applied to diffusion weighted atlas construction

TitleRobust model-based transformation and averaging of diffusion weighted images – applied to diffusion weighted atlas construction
Publication TypeConference Paper
Year of Publication2010
AuthorsNiethammer M, Shi Y, Benzaid S, Sanchez M, Styner M
Conference NameMICCAI, International Workshop on Computational Diffusion MRI (CDMRI' 10)
Abstract

This paper describes a method for model-based averaging of sets of diusion weighted magnetic resonance images (DW-MRI) under space transformations (resulting for example from registration methods). A robust weighted least squares method is developed. Synthetic validation experiments show the improvement of the proposed estimation method in comparison to standard least squares estimation. The developed method is applied to construct an atlas of diffusion weighted images for a set of macaques, allowing for a more  exible representation of average diffusion information compared to standard diffusion tensor atlases.